The Journal of Neuroimmunology:

“Studies from chronic cannabis smokers have provided much of the evidence for immunomodulatory [modifying or regulating the immune system] effects of cannabis in humans…

Cannabinoids can modulate both the function and secretion of cytokines [regulatory proteins] from immune cells.

Therefore, cannabinoids may be considered for treatment of inflammatory disease.“

Sep. 2005 article “Cannabinoids and the Immune System: Potential For The Treatment of Inflammatory Diseases?” by J. Ludovic and Takashi Yamamura

Tod Mikuriya, MD, a psychiatrist and medical coordinator:

“Clinical interviews of over 6500 members at cannabis buyers clubs and patients in my office practice lead to this generalization: Many illnesses or conditions present with both inflammation and muscle spasm. Cannabis is both an antispasmodic and anti inflammatory….

Chronic inflammatory conditions like arthritis and lumbosacral disease responds well to cannabis compared with other analgesics.“

2002 article titled “Medicinal Uses of Cannabis,” published on his website

J. Michael Walker, PhD, Professor of Psychology and the Linda and Jack Gill Chair of Neuroscience at the University of Indiana:

“The spinal cord is loaded with cannabinoid receptors. These cannabinoid compounds [from marijuana] apparently reduce swelling from inflammation [a major symptom of arthritis]. But more than that, they kill the pain from inflammation specifically. They work on the peripheral nerves that carry pain from your joint into the spinal cord.”

Dec. 2000 issue of Arthritis Today